Meta-analysis of ulcerative colitis tissue gene expression: Visualization tool

Online tool for the publication:

Linggi, B., Jairath, V., Zou, G. et al. Meta-analysis of gene expression disease signatures in colonic biopsy tissue from patients with ulcerative colitis. Sci Rep 11, 18243 (2021). https://www.nature.com/articles/s41598-021-97366-5

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Methods: The log2-Fold gene expression changes between ulcerative colitis patients and non-IBD controls were determined for each gene (gene symbol indicated on the top of plot) in individual datasets (labelled as ‘group’) and are indicated by the gray dot and 95% confidence interval range as whiskers. The meta-analysis was calculated using a random effects model shows the meta-log2-Fold change and 95% CI (FoldChange summary, bottom of plot). Datasets used are available in Gene Expression Omnibus: GSE13367, GSE9452, GSE53306, GSE38713, GSE47908, GSE73661, GSE114527, GSE87466. See publication for complete methods.